Analysis of the Results of Proton Radiation Therapy of Patients with Squamous Cell Carcinoma of the Head and Neck

Purpose: To evaluate the severity of early radiation reactions and first results proton therapy treatment patients with squamous cell carcinoma head neck. Material methods: From January 2019 to March 2022, more than 1 400 received on proton-cyclotron complex ProteusPlus235. The search for was carried out in database who oncological diseases FMBA system Russia. study included 62 confirmed unifying model was: mode five-day fractionation SFD 2 Gr, TFD 50 Gy locoregional lymphatic collector zones 60–70 area primary tumor focus high-risk zones. age group is from 18 78 years. According classification ICD10 — 35 were diagnosed C00–C14 “Malignant neoplasms lip, oral cavity pharynx” (56,4 %), 27 C30–C32 upper respiratory organs” (43,5 %). Results: assessment long-term complications requires a systematic uniform approach subject further research, along development optimal patient models by pencil-beam scanning therapy. Conclusions: Proton beam chemoradiotherapy have demonstrated decreasing trends or comparable frequency compared photon In this regard, decision choose method should be based an clinical efficacy, relapse-free event-free survival, which scientific research.